Glypican 3 Antikörper (Middle Region)
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- Target Alle Glypican 3 (GPC3) Antikörper anzeigen
- Glypican 3 (GPC3)
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Glypican 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- FSTIHDSIQY VQKNAGKLTT TIGKLCAHSQ QRQYRSAYYP EDLFIDKKVL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GPC3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GPC3
- Top Product
- Discover our top product GPC3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 580 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." in: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).
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Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." in: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).
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- Target
- Glypican 3 (GPC3)
- Andere Bezeichnung
- GPC3 (GPC3 Produkte)
- Synonyme
- GPC3 antikoerper, sgb antikoerper, dgsx antikoerper, sdys antikoerper, sgbs antikoerper, oci-5 antikoerper, sgbs1 antikoerper, DGSX antikoerper, GTR2-2 antikoerper, MXR7 antikoerper, OCI-5 antikoerper, SDYS antikoerper, SGB antikoerper, SGBS antikoerper, SGBS1 antikoerper, Glypican-3 antikoerper, glypican 3 antikoerper, gpc3 antikoerper, GPC3 antikoerper, Gpc3 antikoerper
- Hintergrund
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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome.
Alias Symbols: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2
Protein Interaction Partner: UBC, WNT3A, WNT7B, IGF2, FGF2,
Protein Size: 580 - Molekulargewicht
- 64 kDa
- Gen-ID
- 2719
- NCBI Accession
- NM_004484, NP_004475
- UniProt
- P51654
- Pathways
- Glycosaminoglycan Metabolic Process
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