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FXYD5 Antikörper (N-Term)

FXYD5 Reaktivität: Human, Maus, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780210
  • Target Alle FXYD5 Antikörper anzeigen
    FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Saccharomyces cerevisiae
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FXYD5 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 16
    • 15
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    LQPTSPTPTW PADETPQPQT QTQQLEGTDG PLVTDPETHK STKAAHPTDD
    Homologie
    Human: 100%, Mouse: 100%, Yeast: 90%
    Produktmerkmale
    This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD5
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 178 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Song, Li, Sun, Zhao: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).

  • Target
    FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
    Andere Bezeichnung
    FXYD5 (FXYD5 Produkte)
    Synonyme
    FXYD5 antikoerper, DYSAD antikoerper, IWU1 antikoerper, KCT1 antikoerper, OIT2 antikoerper, PRO6241 antikoerper, RIC antikoerper, EF-8 antikoerper, Oit2 antikoerper, FXYD domain containing ion transport regulator 5 antikoerper, FXYD domain-containing ion transport regulator 5 antikoerper, FXYD5 antikoerper, Fxyd5 antikoerper
    Hintergrund
    FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.
    Alias Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241
    Protein Interaction Partner: UBC,
    Protein Size: 178
    Molekulargewicht
    20 kDa
    Gen-ID
    53827
    NCBI Accession
    NM_144779, NP_659003
    UniProt
    Q96DB9
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