FXYD5 Antikörper (N-Term)
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- Target Alle FXYD5 Antikörper anzeigen
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FXYD5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LQPTSPTPTW PADETPQPQT QTQQLEGTDG PLVTDPETHK STKAAHPTDD
- Homologie
- Human: 100%, Mouse: 100%, Yeast: 90%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD5
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 178 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).
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Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).
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- Target
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
- Andere Bezeichnung
- FXYD5 (FXYD5 Produkte)
- Synonyme
- FXYD5 antikoerper, DYSAD antikoerper, IWU1 antikoerper, KCT1 antikoerper, OIT2 antikoerper, PRO6241 antikoerper, RIC antikoerper, EF-8 antikoerper, Oit2 antikoerper, FXYD domain containing ion transport regulator 5 antikoerper, FXYD domain-containing ion transport regulator 5 antikoerper, FXYD5 antikoerper, Fxyd5 antikoerper
- Hintergrund
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FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.
Alias Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241
Protein Interaction Partner: UBC,
Protein Size: 178 - Molekulargewicht
- 20 kDa
- Gen-ID
- 53827
- NCBI Accession
- NM_144779, NP_659003
- UniProt
- Q96DB9
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