DHX16 Antikörper (N-Term)

Produktnummer ABIN183550

Produktdetails anti-DHX16 Antikörper

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Pferd, Ziege, Ratte, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KYQLVLEEEE TIEFVRATQL QGDEEPSAPP TSTQAQQKES IQAVRRSLPV

Homologie: Cow: 86%, Goat: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 85%, Rabbit: 77%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DHX16. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX16

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1041 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DHX16

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Andere Bezeichnung: DHX16 (DHX16 Produkte)

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.
Alias Symbols: DBP2, PRP8, Prp2, DDX16, PRPF2, PRO2014
Protein Interaction Partner: NUDCD1, UBC, GPKOW, SF3B2, DHX38, DGCR14, CSNK2A1, XAB2, HELQ, PYROXD1, NAA40, LSM2, MIF4GD, GON4L, WDR44, EHD2, LSM5, LSM6, GCC2, TCEA2, MTR, GSPT1, GABPB1, APP, COIL, SNRNP27, SNRNP40, SIRT7, MEGF10, Bud13, TADA2A, SRRM2, SRRM1,
Protein Size: 1041

Molekulargewicht: 115 kDa

Gen-ID: 8449

NCBI Accession: NM_003587, NP_003578

UniProt: O60231