FUBP1 Antikörper (N-Term)

Produktnummer ABIN2780231

Produktdetails anti-FUBP1 Antikörper

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FUBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: IGKGGETIKQ LQERAGVKMV MIQDGPQNTG ADKPLRITGD PYKVQQAKEM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FUBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 644 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FUBP1 Antikörper (ABIN2780231)

Zheng, Shen, Hu, Roy, Yang, Wang, Zhang, King, Sergi, Liu, Cordat, Tang, Cao, Ali, Chen: "Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation." in: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 9, pp. 2645-57, (2016) (PubMed).

Details zu FUBP1

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Andere Bezeichnung: FUBP1 (FUBP1 Produkte)

Synonyme: FBP antikoerper, FUBP antikoerper, fbp antikoerper, fubp antikoerper, MGC53183 antikoerper, MGC75632 antikoerper, FUBP1 antikoerper, DKFZp468N0812 antikoerper, 9530027K12Rik antikoerper, D3Ertd330e antikoerper, Fubp antikoerper, Fubp4 antikoerper, MGC78835 antikoerper, wu:fa92h11 antikoerper, wu:fb24h11 antikoerper, wu:fc26f06 antikoerper, zgc:66046 antikoerper, far upstream element binding protein 1 antikoerper, far upstream element (FUSE) binding protein 1 S homeolog antikoerper, far upstream element (FUSE) binding protein 1 antikoerper, far upstream element binding protein 1 L homeolog antikoerper, FUBP1 antikoerper, fubp1.S antikoerper, fubp1 antikoerper, Fubp1 antikoerper, fubp1.L antikoerper

Hintergrund: Far upstream element-binding protein activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. FUBP activity may be regulated by alternative splicing, translation efficiency, and posttranslational modification.
Alias Symbols: FBP, FUBP
Protein Interaction Partner: UBC, MDM2, EED, DDX19A, NSUN2, PLD3, ARPC2, ACTR2, ACTR3, ARPC4, HIST1H2BO, SH3GL1, RPA1, PPP5C, LGALS1, CNN2, BAG1, ACO1, AARSD1, GRPEL1, NIF3L1, RPRD1B, CD81, ITGA4, FN1, ATF2, AIMP2, VCAM1, DHX36, MRPL32, MRPL38, MRPL41, MRPL2, CERS2, MRPL42, MRPL46, P
Protein Size: 644

Molekulargewicht: 68 kDa

Gen-ID: 8880

NCBI Accession: NM_003902, NP_003893

UniProt: Q96AE4