ZNF265 Antikörper (N-Term)

Produktnummer ABIN2780239

Produktdetails anti-ZNF265 Antikörper

Target: ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF265 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RCGREKTTEA KMMKAGGTEI GKTLAEKSRG LFSANDWQCK TCSNVNWARR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF265. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF265

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 330 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ZNF265 Antikörper (ABIN2780239)

Wang, Du, Li, Zhang: "Identification of the Zinc Finger Protein ZRANB2 as a Novel Maternal Lipopolysaccharide-binding Protein That Protects Embryos of Zebrafish against Gram-negative Bacterial Infections." in: The Journal of biological chemistry, Vol. 291, Issue 8, pp. 4019-34, (2016) (PubMed).

Details zu ZNF265

Target: ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))

Andere Bezeichnung: ZNF265 (Zranb2 Produkte)

Synonyme: ZNF265 antikoerper, ZRANB2 antikoerper, c4sr antikoerper, zis antikoerper, zis1 antikoerper, zis2 antikoerper, znf265 antikoerper, zranb2 antikoerper, ZIS antikoerper, ZIS1 antikoerper, ZIS2 antikoerper, AI227013 antikoerper, Zfp265 antikoerper, Zis antikoerper, Znf265 antikoerper, zinc finger RANBP2-type containing 2 antikoerper, zinc finger RANBP2-type containing 2 L homeolog antikoerper, zinc finger, RAN-binding domain containing 2 antikoerper, ZRANB2 antikoerper, zranb2.L antikoerper, Zranb2 antikoerper

Hintergrund: ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.
Alias Symbols: ZIS, ZIS1, ZIS2, ZNF265
Protein Interaction Partner: UBC, C18orf25, TBC1D17, CORO1B, PARVA, SWAP70, OSBP, CDK1, FBXL7, SRPK2, SRPK1, CSNK2A1, KIF20A, SMURF1, UBE2B, UBA52, TYMS, TTC1, SULT1A1, SRSF7, PSMA1, PCMT1, UCHL3, UBE2V2, TTC9C, SRXN1, UNK, UBL7, ZNF644, UBQLN1, UBQLN2, UBXN7, TTLL12, UBE2C, AHCYL1,
Protein Size: 330

Molekulargewicht: 37 kDa

Gen-ID: 9406

NCBI Accession: NM_203350, NP_976225

UniProt: Q5VV34