MEFV Antikörper (N-Term)

Produktnummer ABIN2780331

Produktdetails anti-MEFV Antikörper

Target: MEFV (Mediterranean Fever (MEFV))

Bindungsspezifität: N-Term

Reaktivität: Human, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEFV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAKTPSDHLL STLEELVPYD FEKFKFKLQN TSVQKEHSRI PRSQIQRARP

Homologie: Horse: 85%, Human: 100%, Pig: 77%, Rabbit: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against MEFV. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 781 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MEFV

Target: MEFV (Mediterranean Fever (MEFV))

Andere Bezeichnung: MEFV (MEFV Produkte)

Synonyme: pyrin antikoerper, MEFV antikoerper, FMF antikoerper, MEF antikoerper, TRIM20 antikoerper, rfp domain antikoerper, MEFV, pyrin innate immunity regulator antikoerper, Mediterranean fever antikoerper, MEFV antikoerper, Mefv antikoerper

Hintergrund: MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors. This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FMF, MEF, MGC126560, MGC126586, TRIM20
Protein Interaction Partner: COG5, PYCARD, PSTPIP1,
Protein Size: 781

Molekulargewicht: 86 kDa

Gen-ID: 4210

NCBI Accession: NM_000243, NP_000234

UniProt: O15553

Pathways: Positive Regulation of Endopeptidase Activity