TADA2L Antikörper (N-Term)

Produktnummer ABIN2780369

Produktdetails anti-TADA2L Antikörper

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TADA2L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MDRLGPFSND PSDKPPCRGC SSYLMEPYIK CAECGPPPFF LCLQCFTRGF

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TADA2L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TADA2L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 305 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TADA2L Antikörper (ABIN2780369)

Thompson, Yang, Power, Hufschmid, Beveridge, Reid, Ng, Armson, Ryan: "Identification of zoonotic Giardia genotypes in marsupials in Australia." in: Experimental parasitology, Vol. 120, Issue 1, pp. 88-93, (2008) (PubMed).

Details zu TADA2L

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Andere Bezeichnung: TADA2L (TADA2A Produkte)

Synonyme: MGC81519 antikoerper, TADA2A antikoerper, TADA2L antikoerper, ADA2 antikoerper, ADA2A antikoerper, hADA2 antikoerper, AV319371 antikoerper, D030022J10Rik antikoerper, Tada2l antikoerper, tada2l antikoerper, zgc:154057 antikoerper, transcriptional adaptor 2A L homeolog antikoerper, transcriptional adaptor 2A antikoerper, tada2a.L antikoerper, TADA2A antikoerper, Tada2a antikoerper, tada2a antikoerper

Hintergrund: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: ADA2, FLJ12705, KL04P, hADA2, ADA2A, TADA2L
Protein Interaction Partner: MFAP1, MAGOH, KPNA2, FBF1, PRPF31, PPP1R16B, ZFYVE26, SF3A3, FARS2, MTX2, EIF4E2, FAM127C, KLHL38, TTC9C, ZNF564, TEKT4, LOC149950, KLC4, TTC23, GPSM3, CDCA7L, C1orf109, CCHCR1, PRKAB2, ARNT2, USP22, TADA3, HNF4A, LYN, HSP90AA1, KAT2B, MCPH1, PAXIP1, SUPT
Protein Size: 305

Molekulargewicht: 36 kDa

Gen-ID: 6871

NCBI Accession: NM_133439, NP_597683

UniProt: Q9BVJ0

Pathways: Chromatin Binding