EGR4 Antikörper (C-Term)

Produktnummer ABIN2780389

Produktdetails anti-EGR4 Antikörper

Target: EGR4 (Early Growth Response 4 (EGR4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RSDHLTSHVR THTGEKPFAC DVCGRRFARS DEKKRHSKVH LKQKARAEER

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against EGR4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EGR4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 486 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EGR4

Target: EGR4 (Early Growth Response 4 (EGR4))

Andere Bezeichnung: EGR4 (EGR4 Produkte)

Synonyme: EGR4 antikoerper, NGFI-C antikoerper, NGFIC antikoerper, PAT133 antikoerper, NGF1-C antikoerper, pAT133 antikoerper, Egr4l1 antikoerper, early growth response 4 antikoerper, EGR4 antikoerper, Egr4 antikoerper

Hintergrund: The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Alias Symbols: NGFIC, NGFI-C, PAT133
Protein Interaction Partner: NFATC2,
Protein Size: 486

Molekulargewicht: 51 kDa

Gen-ID: 1961

NCBI Accession: NM_001965, NP_001956

UniProt: Q05215