FLI1 Antikörper (N-Term)

Produktnummer ABIN183608

Produktdetails anti-FLI1 Antikörper

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MDGTIKEALS VVSDDQSLFD SAYGAAAHLP KADMTASGSP DYGQPHKINP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FLI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FLI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 452 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FLI1 Antikörper (ABIN183608)

Bujor, Haines, Padilla, Christmann, Junie, Sampaio-Barros, Lafyatis, Trojanowska: "Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1." in: International journal of molecular medicine, Vol. 30, Issue 6, pp. 1473-80, (2012) (PubMed).

Details zu FLI1

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Andere Bezeichnung: FLI1 (FLI1 Produkte)

Synonyme: EWSR2 antikoerper, SIC-1 antikoerper, FLI1 antikoerper, fli antikoerper, Xfli antikoerper, fli1 antikoerper, Xfli1 antikoerper, fli-1 antikoerper, Xfli-1 antikoerper, MGC121593 antikoerper, Fli-1 antikoerper, Sic1 antikoerper, cb855 antikoerper, wu:fc45b11 antikoerper, xlfli antikoerper, Fli-1 proto-oncogene, ETS transcription factor antikoerper, Fli-1 proto-oncogene, ETS transcription factor S homeolog antikoerper, Friend leukemia integration 1 antikoerper, Fli-1 proto-oncogene, ETS transcription factor a antikoerper, Fli-1 proto-oncogene, ETS transcription factor L homeolog antikoerper, FLI1 antikoerper, Fli1 antikoerper, fli1.S antikoerper, fli1 antikoerper, fli1a antikoerper, fli1.L antikoerper

Hintergrund: Friend leukemia integration 1 (Fli-1) is a member of the ETS family of transcriptional regulatory proteins that contain a highly conserved and structurally unique DNA binding ETS domain.
Alias Symbols: EWSR2, SIC-1
Protein Interaction Partner: SOX30, SIAH1, CTBP2, UBC, SMAD9, GATA1, FMNL1, SUMO1, UBE2I, PIAS2, PIAS1, SMAD3, ETV6, KLF1, TDP2, SRF, ERG, EWSR1, ELK1, BRCA1, TGFBR2, STYXL1,
Protein Size: 452

Molekulargewicht: 51 kDa

Gen-ID: 2313

NCBI Accession: NM_002017, NP_002008

UniProt: Q01543