IGHMBP2 Antikörper (N-Term)
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- Target Alle IGHMBP2 Antikörper anzeigen
- IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IGHMBP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QLLELERDAE VEERRSWQEH SSLRELQSRG VCLLKLQVSS QRTGLYGQRL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Ighmbp2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product IGHMBP2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 993 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).
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Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).
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- Target
- IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
- Andere Bezeichnung
- Ighmbp2 (IGHMBP2 Produkte)
- Synonyme
- NV12364 antikoerper, CATF1 antikoerper, HCSA antikoerper, HMN6 antikoerper, SMARD1 antikoerper, SMUBP2 antikoerper, ZFAND7 antikoerper, AEP antikoerper, Catf1 antikoerper, RIPE3b1 antikoerper, Smbp-2 antikoerper, Smbp2 antikoerper, Smubp2 antikoerper, nmd antikoerper, sma antikoerper, RIP-1 antikoerper, RIP1 antikoerper, immunoglobulin mu binding protein 2 antikoerper, IGHMBP2 antikoerper, Ighmbp2 antikoerper, ighmbp2 antikoerper
- Hintergrund
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Ighmbp2 is a 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Ighmbp2 acts as a transcription regulator. Ighmbp2 is required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Ighmbp2 exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Ighmbp2 binds to the insulin II gene RIPE3B enhancer region. Ighmbp2 may be involved in translation.Ighmbp2 is a DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region.Ighmbp2 preferentially binds to the 5'-GGGCT-3' motif. Ighmbp2 interacts with tRNA-Tyr.
Alias Symbols: AEP, Catf1, RIPE3b1, Smbp-2, Smbp2, Smubp2, nmd, sma
Protein Interaction Partner: Gtf3c1, Hnrnph1, Ruvbl1, Abt1, Zbtb14, Tyr, Ighmbp2, Ruvbl2, Hspa1b, Slit3, Robo1,
Protein Size: 993 - Molekulargewicht
- 109 kDa
- Gen-ID
- 20589
- NCBI Accession
- NM_009212, NP_033238
- UniProt
- P40694
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