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IGHMBP2 Antikörper (N-Term)

IGHMBP2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780407
  • Target Alle IGHMBP2 Antikörper anzeigen
    IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
    Bindungsspezifität
    • 15
    • 5
    • 2
    • 2
    • 1
    N-Term
    Reaktivität
    • 26
    • 19
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IGHMBP2 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    QLLELERDAE VEERRSWQEH SSLRELQSRG VCLLKLQVSS QRTGLYGQRL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against Ighmbp2. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Mouse
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    Discover our top product IGHMBP2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 993 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Shababi, Feng, Villalon, Sibigtroth, Osman, Miller, Williams-Simon, Lombardi, Sass, Atkinson, Garcia, Ko, Lorson: "Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).

  • Target
    IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
    Andere Bezeichnung
    Ighmbp2 (IGHMBP2 Produkte)
    Synonyme
    NV12364 antikoerper, CATF1 antikoerper, HCSA antikoerper, HMN6 antikoerper, SMARD1 antikoerper, SMUBP2 antikoerper, ZFAND7 antikoerper, AEP antikoerper, Catf1 antikoerper, RIPE3b1 antikoerper, Smbp-2 antikoerper, Smbp2 antikoerper, Smubp2 antikoerper, nmd antikoerper, sma antikoerper, RIP-1 antikoerper, RIP1 antikoerper, immunoglobulin mu binding protein 2 antikoerper, IGHMBP2 antikoerper, Ighmbp2 antikoerper, ighmbp2 antikoerper
    Hintergrund
    Ighmbp2 is a 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Ighmbp2 acts as a transcription regulator. Ighmbp2 is required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Ighmbp2 exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Ighmbp2 binds to the insulin II gene RIPE3B enhancer region. Ighmbp2 may be involved in translation.Ighmbp2 is a DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region.Ighmbp2 preferentially binds to the 5'-GGGCT-3' motif. Ighmbp2 interacts with tRNA-Tyr.
    Alias Symbols: AEP, Catf1, RIPE3b1, Smbp-2, Smbp2, Smubp2, nmd, sma
    Protein Interaction Partner: Gtf3c1, Hnrnph1, Ruvbl1, Abt1, Zbtb14, Tyr, Ighmbp2, Ruvbl2, Hspa1b, Slit3, Robo1,
    Protein Size: 993
    Molekulargewicht
    109 kDa
    Gen-ID
    20589
    NCBI Accession
    NM_009212, NP_033238
    UniProt
    P40694
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