MAX Antikörper (Middle Region)

Produktnummer ABIN2780421

Produktdetails anti-MAX Antikörper

Target: MAX (MYC Associated Factor X (MAX))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LQTNYPSSDN SLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRKKLRMEAS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MAX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 160 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAX

Target: MAX (MYC Associated Factor X (MAX))

Andere Bezeichnung: MAX (MAX Produkte)

Synonyme: CG9648 antikoerper, Dmel\\CG9648 antikoerper, MAX antikoerper, bHLHd9 antikoerper, dMax antikoerper, dmax antikoerper, max antikoerper, bhlhd4 antikoerper, bhlhd5 antikoerper, bhlhd6 antikoerper, bhlhd7 antikoerper, bhlhd8 antikoerper, xmax2 antikoerper, xmax4 antikoerper, xmax antikoerper, AA960152 antikoerper, AI875693 antikoerper, bHLHd4 antikoerper, bHLHd5 antikoerper, bHLHd6 antikoerper, bHLHd7 antikoerper, bHLHd8 antikoerper, fa92b04 antikoerper, fb52a04 antikoerper, fb95h11 antikoerper, wu:fa92b04 antikoerper, wu:fb52a04 antikoerper, wu:fb95h11 antikoerper, zmax antikoerper, CG9648 gene product from transcript CG9648-RD antikoerper, MYC associated factor X L homeolog antikoerper, MYC associated factor X antikoerper, Max protein antikoerper, MYC associated factor X S homeolog antikoerper, myc associated factor X antikoerper, Max antikoerper, max.L antikoerper, MAX antikoerper, max antikoerper, max.S antikoerper

Hintergrund: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown.
Alias Symbols: orf1, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8
Protein Interaction Partner: USP37, UNC45A, BANP, FBXW11, MXI1, RPL35, TUBA1A, RPL34, GABBR1, FUS, FTH1, MYC, MXD1, MGA, PLIN3, HSP90AA1, TCF3, MYCN, CPSF6, ARL6IP5, KMT2D, HNRNPH2, DYNC1H1, CSTF2, SNIP1, PPP1CC, PPP1CB, PPP1CA, USF1, PCGF6, EP400, DMAP1, WDR5, BRD8, KAT5, MNT, MAX,
Protein Size: 160

Molekulargewicht: 18 kDa

Gen-ID: 4149

NCBI Accession: NM_002382, NP_002373

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases