PBX2 Antikörper (N-Term)

Produktnummer ABIN2780440

Produktdetails anti-PBX2 Antikörper

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PBX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PGGGRGGLGL VSGEPGGPGE PPGGGDPGGG SGGVPGGRGK QDIGDILQQI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PBX2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PBX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 430 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PBX2

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Andere Bezeichnung: PBX2 (PBX2 Produkte)

Synonyme: G17 antikoerper, HOX12 antikoerper, PBX2MHC antikoerper, AU043397 antikoerper, pbxy antikoerper, wu:fb73g03 antikoerper, hox12 antikoerper, pbx2mhc antikoerper, PBX2P1 antikoerper, PBX homeobox 2 antikoerper, pre B cell leukemia homeobox 2 antikoerper, pre-B-cell leukemia homeobox 2 antikoerper, pre-B-cell leukemia homeobox 2 L homeolog antikoerper, PBX2 antikoerper, Pbx2 antikoerper, pbx2 antikoerper, pbx2.L antikoerper

Hintergrund: PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
Alias Symbols: G17, HOX12, PBX2MHC
Protein Interaction Partner: CARD9, HOXA1, SOX2, ELAVL1, COPS6, ZDHHC7, SKIV2L2, SMYD3, MCRS1, CCDC88B, RPS6KC1, PBX2, PBX1, CENPBD1, DCTN3, NUP62, BAIAP2, IKBKAP, UBE2E1, PKNOX1, BLOC1S1, RPL4, HOXB8, HOXA9,
Protein Size: 430

Molekulargewicht: 46 kDa

Gen-ID: 5089

NCBI Accession: NM_002586, NP_002577

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development