HLTF Antikörper (C-Term)

Produktnummer ABIN2780462

Produktdetails anti-HLTF Antikörper

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FIVKDSVEEN MLKIQNKKRE LAAGAFGTKK PNADEMKQAK INEIRTLIDL

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SMARCA3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SMARCA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1009 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HLTF

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Andere Bezeichnung: SMARCA3 (HLTF Produkte)

Hintergrund: SMARCA3 (HLTF) is a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA3 contains a RING finger DNA binding motif. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform which is truncated at the N-terminus as compared to the full-length protein.
Alias Symbols: ZBU1, HLTF1, RNF80, HIP116, SNF2L3, HIP116A, SMARCA3
Protein Interaction Partner: CHFR, UBC, RAD18, SUMO2, RPA3, RPA2, RPA1, WBP4, BRCA1, DTL, SULT1C2, HSPA8, CDK9, NOTCH1, SP3, SP1, SPRTN, Cebpb, ELAVL1, Shprh, RNF146, tat, EWSR1, UBE2Z, RPAP1, USP7, EEF1G, UBE2V2, UBE2N, PCNA,
Protein Size: 1009

Molekulargewicht: 114 kDa

Gen-ID: 6596

NCBI Accession: NM_139048, NP_620636

UniProt: Q14527