IRF7 Antikörper (N-Term)

Produktnummer ABIN2780566

Produktdetails anti-IRF7 Antikörper

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Pferd, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ISSGCYEGLQ WLDEARTCFR VPWKHFARKD LSEADARIFK AWAVARGRWP

Homologie: Cow: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against IRF7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 164 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IRF7

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Andere Bezeichnung: IRF7 (IRF7 Produkte)

Synonyme: wu:fl24c03 antikoerper, zgc:66043 antikoerper, zgc:77947 antikoerper, IRF7 antikoerper, irf7 antikoerper, IRF-7H antikoerper, IRF7A antikoerper, IRF7B antikoerper, IRF7C antikoerper, IRF7H antikoerper, interferon regulatory factor 7 antikoerper, irf7 antikoerper, IRF7 antikoerper, Irf7 antikoerper

Hintergrund: IRF7 is interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue.IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.
Alias Symbols: IRF-7H, IRF7A
Protein Interaction Partner: UBC, SUMO2, SUMO3, TRAF6, NMI, DEAF1, MAFB, SMAD4, SMAD3, SMAD2, vIRF-1, Dlg4, PIAS4, INSR, GCLM, ACADS, MAVS, IRF7, IRF3, IRAK1, TBK1, TRIM28, SUMO1, EP300, CREBBP, TNFAIP3, TRIM21, P4HA1, ARAF, Gbp4, HACE1, CCDC47, TRMT61B, PALD1, TRMT2A, LTN1, TLK2, IQ
Protein Size: 164

Molekulargewicht: 18 kDa

Gen-ID: 3665

NCBI Accession: NM_004031, NP_004022

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagie