Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

COPS2 Antikörper (N-Term)

COPS2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780578
  • Target Alle COPS2 Antikörper anzeigen
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    Bindungsspezifität
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 54
    • 45
    • 41
    • 9
    • 9
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd
    Wirt
    • 51
    • 2
    • 1
    Kaninchen
    Klonalität
    • 52
    • 2
    Polyklonal
    Konjugat
    • 25
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COPS2 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 19
    • 18
    • 13
    • 11
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against COPS2. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human COPS2
    Top Product
    Discover our top product COPS2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 443 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

  • Target
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    Andere Bezeichnung
    COPS2 (COPS2 Produkte)
    Synonyme
    COPS2 antikoerper, ALIEN antikoerper, CSN2 antikoerper, SGN2 antikoerper, TRIP15 antikoerper, wu:fc05f05 antikoerper, wu:fc06g10 antikoerper, wu:fc60f04 antikoerper, wu:fl94f12 antikoerper, zgc:86624 antikoerper, csn2 antikoerper, Tb03.48O8.600 antikoerper, Trip15 antikoerper, AI315723 antikoerper, C85265 antikoerper, Csn2 antikoerper, Sgn2 antikoerper, alien-like antikoerper, ATCSN2 antikoerper, CONSTITUTIVE PHOTOMORPHOGENIC 12 antikoerper, COP12 antikoerper, FUSCA 12 antikoerper, T20P8.4 antikoerper, T20P8_4 antikoerper, COP9 signalosome subunit 2 antikoerper, COP9 signalosome subunit 2 L homeolog antikoerper, COP9 signalosome complex subunit 2 antikoerper, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antikoerper, proteasome family protein antikoerper, COPS2 antikoerper, cops2 antikoerper, cops2.L antikoerper, Tb927.3.2320 antikoerper, AOR_1_576084 antikoerper, PTRG_07106 antikoerper, LOC100283498 antikoerper, Cops2 antikoerper, csn-2 antikoerper, FUS12 antikoerper
    Hintergrund
    COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
    Alias Symbols: ALIEN, CSN2, SGN2, TRIP15
    Protein Interaction Partner: UBC, GPS1, Map3k10, 5830415F09Rik, Taf1b, EP300, Crebbp, cul1, COPS7B, EPB41L1, COPS5, FBXW4, SENP8, vpr, IRF5, COPS4, COPS7A, COPS6, COPS8, COPS3, PMPCA, SEPHS1, EHBP1L1, SLAIN2, GAPVD1, PFKFB2, SEPT2, IRS2, GRK5, DDB2, LRR1, DCAF11, DDA1, RFWD2, DCAF8,
    Protein Size: 443
    Molekulargewicht
    51 kDa
    Gen-ID
    9318
    NCBI Accession
    NM_004236, NP_004227
    UniProt
    P61203
    Pathways
    Zellzyklus
Sie sind hier:
Kundenservice