CIAO1 Antikörper (C-Term)

Produktnummer ABIN2780621

Produktdetails anti-CIAO1 Antikörper

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIAO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HSRTIYDIAW CQLTGALATA CGDDAIRVFQ EDPNSDPQQP TFSLTAHLHQ

Homologie: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against WDR39. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR39

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 339 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CIAO1

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Andere Bezeichnung: WDR39 (CIAO1 Produkte)

Synonyme: CG12797 antikoerper, Dmel\\CG12797 antikoerper, DDBDRAFT_0190506 antikoerper, DDBDRAFT_0266672 antikoerper, DDB_0190506 antikoerper, DDB_0266672 antikoerper, CIA1 antikoerper, WDR39 antikoerper, AW210570 antikoerper, Wdr39 antikoerper, wdr39 antikoerper, zgc:55911 antikoerper, zgc:77394 antikoerper, CG12797 gene product from transcript CG12797-RA antikoerper, WD40 protein Ciao1 antikoerper, CIAO1 antikoerper, WD40 repeat-containing protein antikoerper, cytosolic iron-sulfur assembly component 1 antikoerper, cytosolic iron-sulfur protein assembly 1 antikoerper, Ciao1 antikoerper, cgd1_2230 antikoerper, CC1G_05316 antikoerper, ciao1 antikoerper, CIAO1 antikoerper

Hintergrund: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
Alias Symbols: CIA1, WDR39
Protein Interaction Partner: FAM96B, SF1, MEOX1, FAM96A, MMS19, FMNL2, TOE1, DPP9, FMNL3, CTU1, PPIL4, MAK16, WDR75, NSRP1, EEPD1, WDR61, CDC73, UPF3B, NARFL, YAE1D1, TYW1, ELP2, ELP3, UCKL1, CDKAL1, DPP8, ELP6, PAF1, PLEKHA5, PHAX, RTEL1, ELP4, POLA2, ELP5, WDR43, ERP29, GLRX3, CTR9
Protein Size: 339

Molekulargewicht: 38 kDa

Gen-ID: 9391

NCBI Accession: NM_004804, NP_004795

UniProt: O76071