MED26 Antikörper (N-Term)

Produktnummer ABIN2780622

Produktdetails anti-MED26 Antikörper

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Hund, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED26 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TAAPASPQQI RDRLLQAIDP QSNIRNMVAV LEVISSLEKY PITKEALEET

Homologie: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MED26. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MED26

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 600 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MED26

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Andere Bezeichnung: MED26 (MED26 Produkte)

Synonyme: med26 antikoerper, wu:fe06c07 antikoerper, wu:fi75a09 antikoerper, zgc:55993 antikoerper, CRSP7 antikoerper, CRSP70 antikoerper, 5730493L18Rik antikoerper, AI414941 antikoerper, AW495270 antikoerper, Crsp7 antikoerper, Slc35e1 antikoerper, crsp7 antikoerper, mediator of RNA polymerase II transcription subunit 26 antikoerper, cofactor required for Sp1 transcriptional activation, subunit 7 antikoerper, mediator complex subunit 26 antikoerper, mediator complex subunit 26 L homeolog antikoerper, LOC725023 antikoerper, crsp7 antikoerper, MED26 antikoerper, Med26 antikoerper, med26.L antikoerper

Hintergrund: MED26 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-261 AC024075.4 20290-20550 c 262-726 AF104253.1 1-465 727-3184 AK128435.1 1414-3871
Alias Symbols: CRSP7, CRSP70
Protein Interaction Partner: MED19, MED13, MED12, MED21, MED11, TAF8, MED8, MED30, EAF1, MED10, TAF3, MED25, MED28, ICE2, EAF2, MED29, MED9, MED18, MED15, MED31, MED4, AFF4, MED13L, ICE1, CDK19, ELL2, MED16, MED6, MED20, MED7, MED27, MED17, MED23, MED14, ELL, TAF15, TCEB3, TCEA1, TBP
Protein Size: 600

Molekulargewicht: 65 kDa

Gen-ID: 9441

NCBI Accession: NM_004831, NP_004822

UniProt: O95402

Pathways: Regulation of Lipid Metabolism by PPARalpha