SIM2 Antikörper (N-Term)

Produktnummer ABIN2780639

Produktdetails anti-SIM2 Antikörper

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MKEKSKNAAK TRREKENGEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SIM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 667 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SIM2 Antikörper (ABIN2780639)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Details zu SIM2

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Andere Bezeichnung: SIM2 (SIM2 Produkte)

Synonyme: Xsim2 antikoerper, sim2-A antikoerper, xSim antikoerper, HMC13F06 antikoerper, HMC29C01 antikoerper, SIM antikoerper, bHLHe15 antikoerper, single-minded family bHLH transcription factor 2 S homeolog antikoerper, single-minded family bHLH transcription factor 2 antikoerper, single-minded homolog 2 (Drosophila) antikoerper, sim2.S antikoerper, sim2 antikoerper, SIM2 antikoerper, Sim2 antikoerper

Hintergrund: SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on t
Alias Symbols: MGC119447, SIM, bHLHe15, HMC13F06, HMC29C01
Protein Interaction Partner: Dlg4, HSP90AA1, ARIH1, UBC, PARK2, ARNT, ARNT2, EPO,
Protein Size: 667

Molekulargewicht: 73 kDa

Gen-ID: 6493

NCBI Accession: NM_005069, NP_005060

UniProt: Q14190