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ETS2 Antikörper (Middle Region)

ETS2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Schaf, Ziege, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780665
  • Target Alle ETS2 Antikörper anzeigen
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 46
    • 9
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Schaf, Ziege, Zebrafisch (Danio rerio)
    Wirt
    • 41
    • 6
    Kaninchen
    Klonalität
    • 44
    • 3
    Polyklonal
    Konjugat
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ETS2 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 16
    • 15
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    DPDEVARRWG KRKNKPKMNY EKLSRGLRYY YDKNIIHKTS GKRYVYRFVC
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ETS2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ETS2
    Top Product
    Discover our top product ETS2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 469 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    Andere Bezeichnung
    ETS2 (ETS2 Produkte)
    Synonyme
    0123/09 antikoerper, 0608/07 antikoerper, 0998/12 antikoerper, 3520 antikoerper, CG17077 antikoerper, CG8705 antikoerper, D-Ets-2 antikoerper, D-ets-2 antikoerper, DMPOINT1A antikoerper, Dmel\\CG17077 antikoerper, E(E2F)3D antikoerper, EK3-2 antikoerper, ETS2 antikoerper, EY3-1 antikoerper, Ets antikoerper, Ets2 antikoerper, Ets58AB antikoerper, Ets94F antikoerper, PNT-P1 antikoerper, PNTP1 antikoerper, PNTP2 antikoerper, POINT antikoerper, Pnt antikoerper, Pnt-P1 antikoerper, PntP1 antikoerper, PntP2 antikoerper, Pointed-P1 antikoerper, ets94F antikoerper, l(3)07825 antikoerper, l(3)j1B7 antikoerper, l(3)s118306 antikoerper, png antikoerper, pnt-P1 antikoerper, pnt-P2 antikoerper, pntP2 antikoerper, pntegfr antikoerper, pointed-RC antikoerper, ptd antikoerper, zgc:92106 antikoerper, wu:fe02h08 antikoerper, wu:fk74c05 antikoerper, AU022856 antikoerper, Ets-2 antikoerper, ETS2IT1 antikoerper, c-ets-2 antikoerper, pointed antikoerper, v-ets avian erythroblastosis virus E26 oncogene homolog 2 antikoerper, E26 avian leukemia oncogene 2, 3' domain antikoerper, ETS proto-oncogene 2, transcription factor antikoerper, pnt antikoerper, ets2 antikoerper, Ets2 antikoerper, ETS2 antikoerper
    Hintergrund
    ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ETS2IT1
    Protein Interaction Partner: UBC, RFWD2, TWIST1, POU5F1, TWIST2, ZFYVE9, SRA1, XPO1, TP53, SUMO2, EP300, CREBBP, NCOR1, NCOA3, SRC, ZMYND11, TDP2, STAT5B, CDK10, SMARCA4, JUN, ERG, ETS2, ETS1, NR3C1, GATA3, FOS, SPI1, BRCA1,
    Protein Size: 469
    Molekulargewicht
    53 kDa
    Gen-ID
    2114
    NCBI Accession
    NM_005239, NP_005230
    UniProt
    P15036
    Pathways
    EGFR Signaling Pathway, Myometrial Relaxation and Contraction
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