SMAD4 Antikörper (N-Term)
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- Target Alle SMAD4 Antikörper anzeigen
- SMAD4 (SMAD Family Member 4 (SMAD4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMAD4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- MDNMSITNTP TSNDACLSIV HSLMCHRQGG ESETFAKRAI ESLVKKLKEK
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SMAD4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD4
- Top Product
- Discover our top product SMAD4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 552 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SMAD4 (SMAD Family Member 4 (SMAD4))
- Andere Bezeichnung
- SMAD4 (SMAD4 Produkte)
- Hintergrund
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SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantl
Alias Symbols: DPC4, JIP, MADH4, MYHRS
Protein Interaction Partner: RASSF5, LMO4, SMAD3, SMAD2, SKIL, UBC, NEDD8, SUMO1, SMURF2, SMURF1, TRIM33, CRYAB, COPS5, NLK, OTUB1, SMAD9, UBE2I, FHL3, FHL2, FHL1, CSNK1D, TGFB1I1, SMAD1, NCOR1, SKI, KLF5, IRF7, IRF3, ZNF521, ZNF423, SOX12, SNRNP70, RPL28, RFX1, RELA, RALA, PSMD11, P
Protein Size: 552 - Molekulargewicht
- 60 kDa
- Gen-ID
- 4089
- NCBI Accession
- NM_005359, NP_005350
- UniProt
- Q13485
- Pathways
- Zellzyklus, Chromatin Binding, Autophagie
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