TRIM22 Antikörper (Middle Region)

Produktnummer ABIN405171

Produktdetails anti-TRIM22 Antikörper

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Bindungsspezifität: Middle Region

Reaktivität: Human, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VDVSGKIAWI LGVHSKISSL NKRKSSGFAF DPSVNYSKVY SRYRPQYGYW

Homologie: Human: 100%, Pig: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM22. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM22

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 498 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Andere Bezeichnung: TRIM22 (TRIM22 Produkte)

Hintergrund: TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPSTAF50, RNF94, STAF50
Protein Interaction Partner: EIF4E, UBC, TAB2, CASK, CIC, TRIM22, USP7, RERE, ZZZ3, TAF7, CREB1,
Protein Size: 498

Molekulargewicht: 57 kDa

Gen-ID: 10346

NCBI Accession: NM_006074, NP_006065

UniProt: Q8IYM9