TADA3L Antikörper (C-Term)
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- Target Alle TADA3L (TADA3) Antikörper anzeigen
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TADA3L Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RVRMADNEVM DAFRKIMAAR QKKRTPTKKE KDQAWKTLKE RESILKLLDG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TADA3L. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TADA3L
- Top Product
- Discover our top product TADA3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 432 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
- Andere Bezeichnung
- TADA3L (TADA3 Produkte)
- Synonyme
- ADA3 antikoerper, NGG1 antikoerper, STAF54 antikoerper, TADA3L antikoerper, hADA3 antikoerper, Tada3l antikoerper, 1110004B19Rik antikoerper, AI987856 antikoerper, fa03f04 antikoerper, tada3 antikoerper, wu:fa03f04 antikoerper, zgc:63596 antikoerper, ada3 antikoerper, ada3-A antikoerper, ngg1 antikoerper, tada3l antikoerper, tada3l-a antikoerper, ada3-B antikoerper, tada3l-B antikoerper, transcriptional adaptor 3 antikoerper, transcriptional adapter 3 pseudogene antikoerper, transcriptional adaptor 3 (NGG1 homolog, yeast)-like antikoerper, transcriptional adaptor 3 L homeolog antikoerper, transcriptional adaptor 3 S homeolog antikoerper, TADA3 antikoerper, Tada3 antikoerper, LOC732883 antikoerper, LOC100061462 antikoerper, tada3 antikoerper, LOC100619707 antikoerper, tada3l antikoerper, tada3.L antikoerper, tada3.S antikoerper
- Hintergrund
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Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: ADA3, NGG1, hADA3, TADA3L
Protein Interaction Partner: HEXIM2, CCDC101, CCNC, TP53, USP22, KDM1A, TADA2A, KAT2B, TAF5L, NUP205, SUPT3H, YEATS2, MBIP, WDR5, MAP3K7, DR1, PIAS4, MAGEH1, ING5, XRCC6, SUMO2, SREBF1, TXNRD2, NR1I2, RARA, ESR1, AR, KAT2A, EP300, CTNNB1, ANKRD12, ATXN7, TAF10, FAM107B, ADPGK, HSPA8,
Protein Size: 432 - Molekulargewicht
- 49 kDa
- Gen-ID
- 10474
- NCBI Accession
- NM_006354, NP_006345
- UniProt
- O75528
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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