CREB3 Antikörper (Middle Region)

Produktnummer ABIN2780771

Produktdetails anti-CREB3 Antikörper

Target: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PPLEWPFPDL FSEPLCRGPI LPLQANLTRK GGWLPTGSPS VILQDRYSG

Homologie: Cow: 80%, Dog: 80%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CREB3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CREB3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 371 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CREB3 Antikörper (ABIN2780771)

Mamdani, Alda, Grof, Young, Rouleau, Turecki: "Lithium response and genetic variation in the CREB family of genes." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 500-4, (2008) (PubMed).

Details zu CREB3

Target: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Andere Bezeichnung: CREB3 (CREB3 Produkte)

Synonyme: LUMAN antikoerper, LZIP antikoerper, AU044960 antikoerper, AW538053 antikoerper, C80076 antikoerper, LZIP-1 antikoerper, LZIP-2 antikoerper, Luman antikoerper, creb3 antikoerper, luman antikoerper, lzip antikoerper, cAMP responsive element binding protein 3 antikoerper, cAMP responsive element binding protein 3 S homeolog antikoerper, CREB3 antikoerper, Creb3 antikoerper, creb3.S antikoerper

Hintergrund: CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LUMAN, LZIP, MGC15333, MGC19782
Protein Interaction Partner: COPS5, HCFC1, JUN, CREB3L1, CREB3L3, CREB3, NFE2L3, NFE2L2, DDIT3, CEBPG, ATF4, ATF3, TTLL5, RRAS2, OS9, RABAC1, SQLE, BCAT2, CLP1, UBC, HDAC3, MALL, NFIL3, APPBP2, STX8, BNIP2, CCR1, EMD,
Protein Size: 371

Molekulargewicht: 41 kDa

Gen-ID: 10488

NCBI Accession: NM_006368, NP_006359

UniProt: O43889

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response