ELL Antikörper (N-Term)

Produktnummer ABIN2780787

Produktdetails anti-ELL Antikörper

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Hund, Ratte, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GLSCGRVSDG SKVSVFHVKL TDSALRAFES YRARQDSVSL RPSIRFQGSQ

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ELL. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ELL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 621 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Andere Bezeichnung: ELL (ELL Produkte)

Synonyme: wu:fc60b11 antikoerper, zgc:63836 antikoerper, C19orf17 antikoerper, ELL1 antikoerper, MEN antikoerper, PPP1R68 antikoerper, Ell1 antikoerper, Men antikoerper, elongation factor for RNA polymerase II antikoerper, elongation factor RNA polymerase II antikoerper, ELL antikoerper, ell antikoerper, Ell antikoerper

Hintergrund: ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally, ELL resembles Elongin (SIII), a transcription elongation factor regulated by the product of the von Hippel-Lindau (VHL) tumor suppressor gene.
Alias Symbols: MEN, ELL1, PPP1R68, C19orf17
Protein Interaction Partner: UBC, LOC100363176, SNF8, MCM2, Polr2e, Polr2l, Polr2h, Polr2d, Polr2a, Polr2c, Polr2i, Polr2b, Polr2j, Polr2g, Polr2f, EAF1, ICE2, AFF4, PPP1CA, ICE1, MED26, MLLT3, CDK9, TFPT, KMT2A, MLLT1, USPL1, EAF2, HNRNPU, TP53, ZHX1, SIRT2,
Protein Size: 621

Molekulargewicht: 68 kDa

Gen-ID: 8178

NCBI Accession: NM_006532, NP_006523

UniProt: P55199