TCEA1 Antikörper (N-Term)

Produktnummer ABIN2780804

Produktdetails anti-TCEA1 Antikörper

Target: TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCEA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MEDEVVRFAK KMDKMVQKKN AAGALDLLKE LKNIPMTLEL LQSTRIGMSV

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TCEA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCEA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 301 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TCEA1 Antikörper (ABIN2780804)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu TCEA1

Target: TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))

Andere Bezeichnung: TCEA1 (TCEA1 Produkte)

Synonyme: gtf2s antikoerper, sii antikoerper, tcea antikoerper, tf2s antikoerper, TCEA1 antikoerper, S-II antikoerper, GTF2S antikoerper, SII antikoerper, TCEA antikoerper, TF2S antikoerper, TFIIS antikoerper, fj48e12 antikoerper, wu:fj48e12 antikoerper, zgc:63975 antikoerper, transcription elongation factor A (SII), 1 antikoerper, transcription elongation factor A1 antikoerper, transcription elongation factor A (SII) 1 antikoerper, transcription elongation factor A (SII), 1 L homeolog antikoerper, tcea1 antikoerper, TCEA1 antikoerper, Tcea1 antikoerper, tcea1.L antikoerper

Hintergrund: TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
Alias Symbols: SII, TCEA, TF2S, GTF2S, TFIIS
Protein Interaction Partner: UBC, SORD, PGD, LDHA, CSE1L, BCCIP, CHORDC1, TBP, MCM5, MCM3, MCM2, GTF2H1, GTF2F1, GTF2E1, GTF2B, CDK8, MED26, POLR2C, NAA16, RBM25, SF3B2, UBAC1, POLR2A, APP, PAF1, UBR5, CDK9, LEO1, WDR61, CDC73, RTF1, CTR9, POLR2B, DDX5, INTS1, SF3B3, SNRNP200, SF3A1,
Protein Size: 301

Molekulargewicht: 34 kDa

Gen-ID: 6917

NCBI Accession: NM_006756, NP_006747

UniProt: P23193