Coronin 1a Antikörper (N-Term)
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- Target Alle Coronin 1a (CORO1A) Antikörper anzeigen
- Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Coronin 1a Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFVALI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CORO1A. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CORO1A
- Top Product
- Discover our top product CORO1A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 461 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))
- Andere Bezeichnung
- CORO1A (CORO1A Produkte)
- Synonyme
- CORO1A antikoerper, cor1a antikoerper, Clabp antikoerper, Lmb3 antikoerper, TACO antikoerper, p57 antikoerper, CLABP antikoerper, CLIPINA antikoerper, HCORO1 antikoerper, fj83g12 antikoerper, wu:fj83g12 antikoerper, zgc:63766 antikoerper, coronin 1A antikoerper, Coronin-1A antikoerper, coronin, actin binding protein 1A antikoerper, coronin, actin binding protein, 1A antikoerper, CORO1A antikoerper, cor1a antikoerper, Coro1a antikoerper, coro1a antikoerper
- Hintergrund
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CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages
Alias Symbols: p57, TACO, CLABP, HCORO1, CLIPINA
Protein Interaction Partner: FSD2, GOLGA2, UBC, YTHDC1, SPATA20, POT1, TAB1, GIT2, POLR1C, STAT3, SMARCD1, MAGOH, SMAD3, LMO2, FHL3, FMNL1, NCF4, THBS1, ACTB, DKK1, UBE2G2,
Protein Size: 461 - Molekulargewicht
- 51 kDa
- Gen-ID
- 11151
- NCBI Accession
- NM_007074, NP_009005
- UniProt
- Q2YD73
- Pathways
- Regulation of Actin Filament Polymerization
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