ZNF175 Antikörper (N-Term)

Produktnummer ABIN2780831

Produktdetails anti-ZNF175 Antikörper

Target: ZNF175 (Zinc Finger Protein 175 (ZNF175))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Pferd, Hund, Maus, Schwein, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF175 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FSREEWQQLD PAQRCLYRDV MLELYSHLFA VGYHIPNPEV IFRMLKEKEP

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF175. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF175

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 711 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ZNF175 Antikörper (ABIN2780831)

Carlson, Limoges, Pohlman, Poluektova, Langford, Masliah, Ikezu, Gendelman: "OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis." in: Journal of neuroimmunology, Vol. 150, Issue 1-2, pp. 186-98, (2004) (PubMed).

Details zu ZNF175

Target: ZNF175 (Zinc Finger Protein 175 (ZNF175))

Andere Bezeichnung: ZNF175 (ZNF175 Produkte)

Synonyme: ZNF175 antikoerper, OTK18 antikoerper, zinc finger protein 175 antikoerper, ZNF175 antikoerper

Hintergrund: ZNF175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. As a transcriptional suppressor, this protein plays a role in macrophage control of viral replication during advanced HIV-1 infection.
Alias Symbols: OTK18
Protein Interaction Partner: KRTAP10-7, ZNF250, ZNF264, PSTPIP1, ALAS1, LPXN, UBC, LZTR1, CDC42,
Protein Size: 711

Molekulargewicht: 81 kDa

Gen-ID: 7728

NCBI Accession: NM_007147, NP_009078

UniProt: Q9Y473