STAT1 Antikörper (N-Term)
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- Target Alle STAT1 Antikörper anzeigen
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STAT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- MSQWYELQQL DSKFLEQVHQ LYDDSFPMEI RQYLAQWLEK QDWEHAANDV
- Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against STAT1. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human STAT1
- Top Product
- Discover our top product STAT1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 750 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10555-64, (2015) (PubMed).
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Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10555-64, (2015) (PubMed).
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- Target
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- Andere Bezeichnung
- STAT1 (STAT1 Produkte)
- Synonyme
- CANDF7 antikoerper, ISGF-3 antikoerper, STAT91 antikoerper, 2010005J02Rik antikoerper, AA408197 antikoerper, XStat1 antikoerper, STAT4 antikoerper, DD6G4-4 antikoerper, STAT antikoerper, STAT1 antikoerper, dZ182H3.3 antikoerper, si:by134g18.2 antikoerper, si:by51f19.1 antikoerper, si:dz182h3.3 antikoerper, si:dz199m19.1 antikoerper, si:dz73o4.2 antikoerper, stat1 antikoerper, signal transducer and activator of transcription 1 antikoerper, signal transducer and activator of transcription 1 L homeolog antikoerper, signal transducer and activator of transcription 1, 91kDa antikoerper, signal transducer and activator of transcription 4 antikoerper, signal transducer and activator of transcription 1a antikoerper, STAT1 antikoerper, Stat1 antikoerper, stat1.L antikoerper, stat4 antikoerper, stat1a antikoerper
- Hintergrund
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STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: DKFZp686B04100, ISGF-3, STAT91, CANDF7
Protein Interaction Partner: HUWE1, ISG15, PIAS1, UBC, STAT1, EIF1AD, OTUD4, LMO2, GNB2, DTX3L, EGFR, NAA15, SNX6, CAND1, VPS29, GSPT2, JMJD6, RTF1, HSPA4L, ATG7, YAP1, PAWR, KARS, IDE, CTTN, VPS26A, HIRIP3, NAA10, TSNAX, TBCD, SNX2, SNX1, SHMT2, SHMT1, SARS, ATP6V1C1, APEH, USP13, E
Protein Size: 750 - Molekulargewicht
- 87 kDa
- Gen-ID
- 6772
- NCBI Accession
- NM_007315, NP_009330
- UniProt
- P42224
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
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