LDOC1 Antikörper (N-Term)

Produktnummer ABIN2780876

Produktdetails anti-LDOC1 Antikörper

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDOC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Sequenz: MVDELVLLLH ALLMRHRALS IENSQLMEQL RLLVCERASL LRQVRPPSCP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against LDOC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 146 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LDOC1

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Andere Bezeichnung: LDOC1 (LDOC1 Produkte)

Hintergrund: LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Alias Symbols: BCUR1, Mar7, Mart7
Protein Interaction Partner: LENG1, TTC23, MEAF6, SH2D4A, CTNNBL1, DPPA4, FAM90A1, C1orf109, FAM208B, TBC1D7, PRPF31, LDOC1, PEG10, NXF1, ZBTB24, HDAC4, ATP6V1G1, HGS, LATS1, RAB29, TNNT1, TMSB4XP1, SDCBP, DPF2, PSMA1, MFAP1, BARD1, ATF4, AES, ZNF774, ZNF564, HAUS1, ZGPAT, CCDC33, IN
Protein Size: 146

Molekulargewicht: 17 kDa

Gen-ID: 23641

NCBI Accession: NM_012317, NP_036449

UniProt: O95751