BRD4 Antikörper (C-Term)

Produktnummer ABIN2780921

Produktdetails anti-BRD4 Antikörper

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Sequenz: EIEIDFETLK PSTLRELERY VTSCLRKKRK PQAEKVDVIA GSSKMKGFSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BRD4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BRD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 722 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Andere Bezeichnung: BRD4 (BRD4 Produkte)

Synonyme: brd4-b antikoerper, BRD4 antikoerper, fb18g03 antikoerper, wu:fb18g03 antikoerper, CAP antikoerper, HUNK1 antikoerper, HUNKI antikoerper, MCAP antikoerper, Brd5 antikoerper, WI-11513 antikoerper, bromodomain containing 4 L homeolog antikoerper, bromodomain containing 4 antikoerper, bromodomain-containing protein 4 antikoerper, brd4.L antikoerper, BRD4 antikoerper, brd4 antikoerper, LOC100409351 antikoerper, Brd4 antikoerper

Hintergrund: BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Alias Symbols: CAP, HUNKI, MCAP, HUNK1
Protein Interaction Partner: AFF1, CDK9, CCNT1, STAT3, JMJD6, TCERG1, HEXIM1, RN7SK, PRPF40A, vif, RPL6, MYC, MLLT1, ELAVL1, SUMO2, UBC, YWHAZ, KAT8, C8orf33, MESDC2, HIST1H4A, HIST1H3A, YWHAE, MED1, EP300, KDM5B, C7orf25, CHFR, CLDN1, RFC1, RFC4, HIST2H3C, HIST2H4A, MED12, MED24, ME
Protein Size: 722

Molekulargewicht: 80 kDa

Gen-ID: 23476

NCBI Accession: NM_014299, NP_055114

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interaktom