KLHL5 Antikörper (N-Term)

Produktnummer ABIN2780990

Produktdetails anti-KLHL5 Antikörper

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLHL5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MSGSRKEFDV KQILKIRWRW FGHQASSPNS TVDSQQGEFW NRGQTGANGG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against KLHL5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human KLHL5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 709 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-KLHL5 Antikörper (ABIN2780990)

Nagalla, Shaw, Kong, Kondkar, Edelstein, Ma, Chen, McKnight, López, Yang, Jin, Bray, Leal, Dong, Bray: "Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity." in: Blood, Vol. 117, Issue 19, pp. 5189-97, (2011) (PubMed).

Details zu KLHL5

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Andere Bezeichnung: KLHL5 (KLHL5 Produkte)

Synonyme: 1300013C10Rik antikoerper, kelch-like 5 antikoerper, kelch like family member 5 antikoerper, kelch-like family member 5 antikoerper, Klhl5 antikoerper, KLHL5 antikoerper, klhl5 antikoerper

Hintergrund: The kelch-repeat protein family is a recently found new kind of actin-binding protein. It is characterized by tandemly arranged motifs of about 50 amino acids. Most members of the kelch-repeat family were cytoskeletal proteins implicated in various cellular processes, such as actin cytoskeleton interaction, cytoplasmic sequestration of transcription factors and cell morphology. During the large-scale sequencing analysis of a human fetal brain cDNA library we found a novel kelch-like protein gene 5, KLHL5, KLHL5 has high identity with Drosophila kelch protein and many other family members. A novel splicing variants of KLHL5, named KLHL5b and the expression pattern of KLHL5b in many tissues.
Alias Symbols: -
Protein Interaction Partner: FUS, CUL3, UBC, MAP1LC3B, GABARAPL2, TK1, SMN1,
Protein Size: 709

Molekulargewicht: 79 kDa

Gen-ID: 51088

NCBI Accession: NM_001007075, NP_001007076

UniProt: Q96PQ7