PRRX2 Antikörper (N-Term)

Produktnummer ABIN2781006

Produktdetails anti-PRRX2 Antikörper

Target: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Bindungsspezifität: N-Term

Reaktivität: Maus, Human, Ratte, Pferd, Schwein, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRRX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RKNFSVSHLL DLEEVAAAGR LAARPGARAE AREGAAREPS GGSSGSEAAP

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 79%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PRRX2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRRX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 253 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PRRX2 Antikörper (ABIN2781006)

Tokutomi, Araki, Kataoka, Yamamoto, Kim-Mitsuyama: "Oxidation of Prx2 and phosphorylation of GRP58 by angiotensin II in human coronary smooth muscle cells identified by 2D-DIGE analysis." in: Biochemical and biophysical research communications, Vol. 364, Issue 4, pp. 822-30, (2007) (PubMed).

Details zu PRRX2

Target: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Andere Bezeichnung: PRRX2 (PRRX2 Produkte)

Synonyme: Prx2 antikoerper, PRRX2 antikoerper, PMX2 antikoerper, PRX2 antikoerper, S8 antikoerper, (S8) antikoerper, PRX-2 antikoerper, paired related homeobox 2 antikoerper, Prrx2 antikoerper, PRRX2 antikoerper

Hintergrund: PRRX2 is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
Alias Symbols: MGC19843, PMX2, PRX2
Protein Interaction Partner: SOX10,
Protein Size: 253

Molekulargewicht: 27 kDa

Gen-ID: 51450

NCBI Accession: NM_016307, NP_057391

UniProt: Q99811