GTF2IRD1 Antikörper (N-Term)

Produktnummer ABIN2781009

Produktdetails anti-GTF2IRD1 Antikörper

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2IRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MALLGKRCDV PTNGCGPDRW NSAFTRKDEI ITSLVSALDS MCSALSKLNA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2IRD1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2IRD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 959 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GTF2IRD1

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Andere Bezeichnung: GTF2IRD1 (GTF2IRD1 Produkte)

Synonyme: Gtf3 antikoerper, 1700012P16Rik antikoerper, BEN antikoerper, Cream1 antikoerper, ESTM9 antikoerper, GTF3 antikoerper, Gtf2il antikoerper, MusTRD1 antikoerper, Tg(Alb1-Myc)166.8Sst antikoerper, WBSCR11 antikoerper, X83320 antikoerper, GTF2IRD1 antikoerper, CREAM1 antikoerper, MUSTRD1 antikoerper, RBAP2 antikoerper, WBS antikoerper, WBSCR12 antikoerper, hMusTRD1alpha1 antikoerper, XBEN antikoerper, XWBSCR11 antikoerper, cream1 antikoerper, gtf3 antikoerper, mustrd1 antikoerper, rbap2 antikoerper, wbs antikoerper, wbscr11 antikoerper, wbscr12 antikoerper, GTF2I repeat domain containing 1 antikoerper, general transcription factor II I repeat domain-containing 1 antikoerper, general transcription factor II-I repeat domain-containing protein 1 antikoerper, GTF2I repeat domain containing 1 S homeolog antikoerper, GTF2IRD1 antikoerper, Gtf2ird1 antikoerper, gtf2ird1 antikoerper, LOC100461122 antikoerper, gtf2ird1.S antikoerper

Hintergrund: GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. GTF2IRD1 is related to Williams-Beuren syndrome, a multisystem developmental disorder. Western blots using three different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.
Alias Symbols: CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12, hMusTRD1alpha1, BEN, WBS
Protein Interaction Partner: UBC, SUMO2, USF1, HDAC3, SMAD2, EXOSC4, CDK20, PIAS2, SMAD3, NFI1,
Protein Size: 959

Molekulargewicht: 106 kDa

Gen-ID: 9569

NCBI Accession: NM_016328, NP_057412

UniProt: Q9UHL9