PHF21A Antikörper (N-Term)

Produktnummer ABIN2781018

Produktdetails anti-PHF21A Antikörper

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF21A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MELQTLQEAL KVEIQVHQKL VAQMKQDPQN ADLKKQLHEL QAKITALSEK

Homologie: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHF21A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF21A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 634 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PHF21A Antikörper (ABIN2781018)

Hailesellasse Sene, Porter, Palidwor, Perez-Iratxeta, Muro, Campbell, Rudnicki, Andrade-Navarro: "Gene function in early mouse embryonic stem cell differentiation." in: BMC genomics, Vol. 8, pp. 85, (2007) (PubMed).

Details zu PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Andere Bezeichnung: PHF21A (PHF21A Produkte)

Hintergrund: PHF21A (BHC80) is a component of a BRAF35/histone deacetylase complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS). BHC80 is a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC, see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM].
Alias Symbols: BHC80, BM-006, KIAA1696
Protein Interaction Partner: KRT40, BANP, NUP62, ZYX, TRAF1, FHL3, HDAC2, HDAC1, HIST3H3, HMG20B, ELAVL1, SUMO2, HIST2H3C, ESCO2, KDM1A, TAF10, RCOR1, LPXN, GTF2I,
Protein Size: 634

Molekulargewicht: 70 kDa

Gen-ID: 51317

NCBI Accession: NM_016621, NP_057705

Pathways: Feeding Behaviour