POLE4 Antikörper (N-Term)

Produktnummer ABIN2781088

Produktdetails anti-POLE4 Antikörper

Target: POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Hund, Pferd, Meerschweinchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLE4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAAAAAAGSG TPREEEGPAG EAAASQPQAP TSVPGARLSR LPLARVKALV

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against POLE4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POLE4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 117 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu POLE4

Target: POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))

Andere Bezeichnung: POLE4 (POLE4 Produkte)

Synonyme: 2400007P05Rik antikoerper, 5830430F06Rik antikoerper, YHHQ1 antikoerper, p12 antikoerper, DNA polymerase epsilon 4, accessory subunit antikoerper, polymerase (DNA-directed), epsilon 4, accessory subunit antikoerper, polymerase (DNA-directed), epsilon 4 (p12 subunit) antikoerper, Pole4 antikoerper, POLE4 antikoerper, pole4 antikoerper

Hintergrund: POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Alias Symbols: p12, YHHQ1
Protein Interaction Partner: NFYB, gag-pol, NUP133, POLE3, MAP3K7, UBC, YEATS2, POLE4, UBE3A, HSPA13, POLE2, POLE, RAD17,
Protein Size: 117

Molekulargewicht: 12 kDa

Gen-ID: 56655

NCBI Accession: NM_019896, NP_063949

UniProt: Q9NR33

Pathways: DNA Reparatur