REXO4 Antikörper (N-Term)
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- Target Alle REXO4 Antikörper anzeigen
- REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser REXO4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MGKAKVPASK RAPSSPVAKP GPVKTLTRKK NKKKKRFWKS KAREVSKKPA
- Homologie
- Human: 100%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against REXO4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human REXO4
- Top Product
- Discover our top product REXO4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 422 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
- Andere Bezeichnung
- REXO4 (REXO4 Produkte)
- Synonyme
- REXO4 antikoerper, REX4 antikoerper, XPMC2 antikoerper, XPMC2H antikoerper, Gm111 antikoerper, Xpmc2h antikoerper, xpmc2 antikoerper, im:7156740 antikoerper, si:ch73-209e20.4 antikoerper, REX4 homolog, 3'-5' exonuclease antikoerper, REX4, 3'-5' exonuclease antikoerper, RNA exonuclease 4 antikoerper, putative 3'-5' exonuclease antikoerper, REXO4 antikoerper, Rexo4 antikoerper, LOC100229203 antikoerper, rexo4.S antikoerper, CAALFM_C112440WA antikoerper, rexo4 antikoerper
- Hintergrund
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The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Alias Symbols: REX4, XPMC2, XPMC2H
Protein Interaction Partner: UBC, SIRT7, ESR2, ESR1,
Protein Size: 422 - Molekulargewicht
- 47 kDa
- Gen-ID
- 57109
- NCBI Accession
- NM_020385, NP_065118
- UniProt
- Q9GZR2
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