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PRDM12 Antikörper (C-Term)

PRDM12 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781154
  • Target Alle PRDM12 Antikörper anzeigen
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 22
    • 17
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Schwein
    Wirt
    • 20
    • 2
    Kaninchen
    Klonalität
    • 20
    • 2
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PRDM12 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    NHVRLHTGER PYKCQVCQSA YSQLAGLRAH QKSARHRPPS TALQAHSPAL
    Homologie
    Cow: 93%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM12
    Top Product
    Discover our top product PRDM12 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 367 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Andere Bezeichnung
    PRDM12 (PRDM12 Produkte)
    Synonyme
    PRDM12 antikoerper, prdm12 antikoerper, MGC146714 antikoerper, PFM9 antikoerper, pfm9 antikoerper, Gm998 antikoerper, PR/SET domain 12 antikoerper, PR domain containing 12 antikoerper, PR domain containing 12 L homeolog antikoerper, PR domain containing 12a antikoerper, PRDM12 antikoerper, prdm12 antikoerper, prdm12.L antikoerper, Prdm12 antikoerper, prdm12a antikoerper
    Hintergrund
    PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
    Alias Symbols: PFM9
    Protein Size: 367
    Molekulargewicht
    40 kDa
    Gen-ID
    59335
    NCBI Accession
    NM_021619, NP_067632
    UniProt
    Q9H4Q4
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