CBLL1 Antikörper (C-Term)

Produktnummer ABIN2781231

Produktdetails anti-CBLL1 Antikörper

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PFTQPGGMSP GIWPAPRGPP PPPRLQGPPS QTPLPGPHHP DQTRYRPYYQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CBLL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CBLL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 491 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CBLL1 Antikörper (ABIN2781231)

Horiuchi, Kawamura, Iwanari, Ohashi, Naito, Kodama, Hamakubo: "Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33292-302, (2013) (PubMed).

Details zu CBLL1

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Andere Bezeichnung: CBLL1 (CBLL1 Produkte)

Synonyme: HAKAI antikoerper, RNF188 antikoerper, zgc:55308 antikoerper, CBLL1 antikoerper, AI467391 antikoerper, Hakai antikoerper, c-Cbl-like antikoerper, cbll1 antikoerper, hakai antikoerper, rnf188 antikoerper, Cbl proto-oncogene like 1 antikoerper, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase S homeolog antikoerper, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase antikoerper, Casitas B-lineage lymphoma-like 1 antikoerper, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase L homeolog antikoerper, CBLL1 antikoerper, cbll1.S antikoerper, Cbll1 antikoerper, cbll1 antikoerper, cbll1.L antikoerper

Hintergrund: Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].
Alias Symbols: HAKAI, RNF188
Protein Interaction Partner: DGCR6, SUMO1, UBC, CDH1, RNF2, YWHAQ, SFPQ, Cbll1, ESR1, CTTN, DOK1, SRC, CDC42,
Protein Size: 491

Molekulargewicht: 55 kDa

Gen-ID: 79872

NCBI Accession: NM_024814, NP_079090

UniProt: Q75N03