HECTD2 Antikörper (C-Term)

Produktnummer ABIN2781287

Produktdetails anti-HECTD2 Antikörper

Target: HECTD2 (HECT Domain Containing 2 (HECTD2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HECTD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TDLTIKYFWD VVLGFPLDLQ KKLLHFTTGS DRVPVGGMAD LNFKISKNET

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HECTD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HECTD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 776 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HECTD2 Antikörper (ABIN2781287)

Sun, Wang, He, Sweeney, Liu, Brown, Balk, Lee, Kantoff: "MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A." in: Oncogene, Vol. 33, Issue 21, pp. 2790-800, (2014) (PubMed).

Details zu HECTD2

Target: HECTD2 (HECT Domain Containing 2 (HECTD2))

Andere Bezeichnung: HECTD2 (HECTD2 Produkte)

Synonyme: hmm77879 antikoerper, HECTD2 antikoerper, DKFZp459J1430 antikoerper, 4921524L07 antikoerper, A630025O09Rik antikoerper, AW212605 antikoerper, HECT domain E3 ubiquitin protein ligase 2 antikoerper, HECT domain containing E3 ubiquitin protein ligase 2 antikoerper, Probable E3 ubiquitin-protein ligase HECTD2 antikoerper, HECT domain containing 2 antikoerper, HECTD2 antikoerper, hectd2 antikoerper, hecd2 antikoerper, Hectd2 antikoerper

Hintergrund: HECTD2 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Alias Symbols: FLJ16050
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 776

Molekulargewicht: 88 kDa

Gen-ID: 143279

NCBI Accession: NM_182765, NP_877497

UniProt: Q5RD78