MTA2 Antikörper (C-Term)

Produktnummer ABIN2781484

Produktdetails anti-MTA2 Antikörper

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ALTHLEMRRA ARRPNLPLKV KPTLIAVRPP VPLPAPSHPA STNEPIVLED

Homologie: Cow: 88%, Dog: 94%, Goat: 88%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 94%, Pig: 94%, Rabbit: 100%, Rat: 94%

Produktmerkmale: This is a rabbit polyclonal antibody against MTA2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MTA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 327 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MTA2 Antikörper (ABIN2781484)

Schiene-Fischer, Yu: "Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases." in: FEBS letters, Vol. 495, Issue 1-2, pp. 1-6, (2001) (PubMed).

Details zu MTA2

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Andere Bezeichnung: MTA2 (MTA2 Produkte)

Synonyme: MTA1L1 antikoerper, PID antikoerper, fd61b05 antikoerper, wu:fd61b05 antikoerper, wu:fi29g02 antikoerper, zgc:63487 antikoerper, pid antikoerper, mta1l1 antikoerper, MTA2 antikoerper, DKFZp470E0911 antikoerper, AW550797 antikoerper, Mata1l1 antikoerper, Mta1l1 antikoerper, mmta2 antikoerper, metastasis associated 1 family member 2 antikoerper, metastasis associated 1 family, member 2 antikoerper, metastasis-associated gene family, member 2 antikoerper, metastasis associated 1 family member 2 L homeolog antikoerper, MTA2 antikoerper, mta2 antikoerper, Mta2 antikoerper, mta2.L antikoerper

Hintergrund: MTA2 modulates the enzymatic activity of the histone deacetylase core complex.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. This gene is found to be deleted in Williams syndrome.
Alias Symbols: DKFZp686F2281, MTA1L1, PID
Protein Interaction Partner: vpr, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, ZBTB16, UBC, RARA, ZBTB1, RNF2, GPHN, HNRNPR, TRIM28, PPP4R1, ROCK2, SPAG9, POLR2C, POLR2A, MAP4, RPP25, LSM8, GET4, LARP7, CD2AP, NR3C1, MTOR, EHBP1L1, RABEP2, BRCC3, SMEK1, ZGPAT, HDAC1, HDAC2, CSNK1E, MTA3, UBE3
Protein Size: 327

Molekulargewicht: 36 kDa

Gen-ID: 9219

NCBI Accession: NM_003602, NP_004730

UniProt: O94776

Pathways: Chromatin Binding