ORCTL-2/SLC22A18 Antikörper (N-Term)

Produktnummer ABIN2781574

Produktdetails anti-ORCTL-2/SLC22A18 Antikörper

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORCTL-2/SLC22A18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AASSPALPGV YLLFASRLPG ALMHTLPAAQ MVITDLSAPE ERPAALGRLG

Homologie: Cow: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC22A18. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A18

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 424 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ORCTL-2/SLC22A18

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Andere Bezeichnung: SLC22A18 (SLC22A18 Produkte)

Hintergrund: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney.This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.
Alias Symbols: BWR1A, BWSCR1A, DKFZp667A184, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A
Protein Interaction Partner: RNF167, UBC,
Protein Size: 424

Molekulargewicht: 45 kDa

Gen-ID: 5002

NCBI Accession: NM_002555, NP_002546

UniProt: Q96BI1