SLC26A5 Antikörper (Middle Region)

Produktnummer ABIN2781751

Produktdetails anti-SLC26A5 Antikörper

Target: SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC26A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FSVTISMAKT LANKHGYQVD GNQELIALGL CNSIGSLFQT FSISCSLSRS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC26A5. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC26A5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 744 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SLC26A5

Target: SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))

Andere Bezeichnung: SLC26A5 (SLC26A5 Produkte)

Synonyme: pres antikoerper, fb73d12 antikoerper, fb74g12 antikoerper, wu:fb73d12 antikoerper, wu:fb74g12 antikoerper, DFNB61 antikoerper, PRES antikoerper, Pres antikoerper, prestin antikoerper, solute carrier family 26 (anion exchanger), member 5 antikoerper, solute carrier family 26 member 5 antikoerper, solute carrier family 26, member 5 antikoerper, slc26a5 antikoerper, SLC26A5 antikoerper, Slc26a5 antikoerper

Hintergrund: SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DFNB61, MGC118886, MGC118887, MGC118888, MGC118889, PRES
Protein Size: 744

Molekulargewicht: 81 kDa

Gen-ID: 375611

NCBI Accession: NM_198999, NP_945350

UniProt: P58743

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport