EXT2 Antikörper (N-Term)

Produktnummer ABIN2781795

Produktdetails anti-EXT2 Antikörper

Target: EXT2 (Exostosin 2 (EXT2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NELLMAISDS DYYTDDINRA CLFVPSIDVL NQNTLRIKET AQAMAQLSRW

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EXT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 718 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EXT2

Target: EXT2 (Exostosin 2 (EXT2))

Andere Bezeichnung: EXT2 (EXT2 Produkte)

Synonyme: SOTV antikoerper, AI893565 antikoerper, EXT2 antikoerper, ext2 antikoerper, exostosin glycosyltransferase 2 antikoerper, exostoses (multiple) 2 antikoerper, exostoses (multiple) 3 antikoerper, exostosin glycosyltransferase 2 L homeolog antikoerper, EXT2 antikoerper, Ext2 antikoerper, EXT3 antikoerper, ext2.L antikoerper

Hintergrund: EXT2 is one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis.This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: SOTV
Protein Interaction Partner: UBC, GSKIP, SLC22A2, CDKN1A, ANXA7, TK1, SMN1, PFDN1, GALNT5, TRAP1, EXT2, EXT1, CLEC2L, CRB1, HYOU1, STK16, TCEB1, SNCG, RPS29, HNF4A, FABP4, CNTF,
Protein Size: 718

Molekulargewicht: 82 kDa

Gen-ID: 2132

NCBI Accession: NM_000401, NP_000392

UniProt: Q93063

Pathways: Glycosaminoglycan Metabolic Process