FGG Antikörper (Middle Region)

Produktnummer ABIN2781808

Produktdetails anti-FGG Antikörper

Target: FGG (Fibrinogen gamma Chain (FGG))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GWTVFQKRLD GSVDFKKNWI QYKEGFGHLS PTGTTEFWLG NEKIHLISTQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against FGG. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 437 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Andere Bezeichnung: FGG (FGG Produkte)

Synonyme: FXII antikoerper, HAF antikoerper, 3010002H13Rik antikoerper, AI256424 antikoerper, fibrinogen antikoerper, FGG antikoerper, LOC100220680 antikoerper, fb60h05 antikoerper, fb62e01 antikoerper, wu:fb60h05 antikoerper, wu:fb62e01 antikoerper, zgc:56023 antikoerper, fibrinogen gamma chain antikoerper, coagulation factor XII (Hageman factor) antikoerper, fibrinogen gamma chain L homeolog antikoerper, FGG antikoerper, F12 antikoerper, fgg antikoerper, Fgg antikoerper, fgg.L antikoerper, CpipJ_CPIJ006387 antikoerper, CpipJ_CPIJ010087 antikoerper

Hintergrund: FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: -
Protein Interaction Partner: SUMO2, ASB12, ASB7, ASB6, FN1, VKORC1, KHDRBS2, SERPINA5, VTN, ITGB3, ICAM1, FGG, FGB, FGA, F13B, F13A1, ITGAM,
Protein Size: 437

Molekulargewicht: 46 kDa

Gen-ID: 2266

NCBI Accession: NM_000509, NP_000500

UniProt: P02679