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GGCX Antikörper (Middle Region)

GGCX Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781826
  • Target Alle GGCX Antikörper anzeigen
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 34
    • 21
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Pferd
    Wirt
    • 47
    • 1
    • 1
    Kaninchen
    Klonalität
    • 49
    Polyklonal
    Konjugat
    • 14
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GGCX Antikörper ist unkonjugiert
    Applikation
    • 25
    • 23
    • 18
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    FLLRKLYVFR RSFLMTCISL RNLILGRPSL EQLAQEVTYA NLRPFEAVGE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against GGCX. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GGCX
    Top Product
    Discover our top product GGCX Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 758 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    Andere Bezeichnung
    GGCX (GGCX Produkte)
    Synonyme
    GGCX antikoerper, cb751 antikoerper, si:ch1073-230p18.3 antikoerper, zgc:158736 antikoerper, ggcx antikoerper, GGC antikoerper, vkcfd1 antikoerper, CG13927 antikoerper, DgammaC antikoerper, Dmel\\CG13927 antikoerper, dGC antikoerper, dgammaC antikoerper, gammaC antikoerper, VKCFD1 antikoerper, gamma-glutamyl carboxylase antikoerper, gamma-glutamyl carboxylase L homeolog antikoerper, GGCX antikoerper, ggcx antikoerper, GC antikoerper, sce5891 antikoerper, ggcx.L antikoerper, Ggcx antikoerper
    Hintergrund
    GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ26629, VKCFD1
    Protein Interaction Partner: UBC, DCP2, FBXO6, F9, F10, F7, F2, PROC, BGLAP,
    Protein Size: 758
    Molekulargewicht
    87 kDa
    Gen-ID
    2677
    NCBI Accession
    NM_000821, NP_000812
    UniProt
    P38435
    Pathways
    SARS-CoV-2 Protein Interaktom
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