GGCX Antikörper (Middle Region)

Produktnummer ABIN2781826

Produktdetails anti-GGCX Antikörper

Target: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GGCX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FLLRKLYVFR RSFLMTCISL RNLILGRPSL EQLAQEVTYA NLRPFEAVGE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GGCX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GGCX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 758 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GGCX

Target: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Andere Bezeichnung: GGCX (GGCX Produkte)

Synonyme: GGCX antikoerper, cb751 antikoerper, si:ch1073-230p18.3 antikoerper, zgc:158736 antikoerper, ggcx antikoerper, GGC antikoerper, vkcfd1 antikoerper, CG13927 antikoerper, DgammaC antikoerper, Dmel\\CG13927 antikoerper, dGC antikoerper, dgammaC antikoerper, gammaC antikoerper, VKCFD1 antikoerper, gamma-glutamyl carboxylase antikoerper, gamma-glutamyl carboxylase L homeolog antikoerper, GGCX antikoerper, ggcx antikoerper, GC antikoerper, sce5891 antikoerper, ggcx.L antikoerper, Ggcx antikoerper

Hintergrund: GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ26629, VKCFD1
Protein Interaction Partner: UBC, DCP2, FBXO6, F9, F10, F7, F2, PROC, BGLAP,
Protein Size: 758

Molekulargewicht: 87 kDa

Gen-ID: 2677

NCBI Accession: NM_000821, NP_000812

UniProt: P38435

Pathways: SARS-CoV-2 Protein Interaktom