LCLAT1 Antikörper (Middle Region)

Produktnummer ABIN2781857

Produktdetails anti-LCLAT1 Antikörper

Target: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Bindungsspezifität: Middle Region

Reaktivität: Maus, Human, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCLAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LYCAT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 376 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LCLAT1 Antikörper (ABIN2781857)

Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

Details zu LCLAT1

Target: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Andere Bezeichnung: LYCAT (LCLAT1 Produkte)

Synonyme: lclat1 antikoerper, zgc:77380 antikoerper, wu:fj17g04 antikoerper, LYCAT antikoerper, lycat antikoerper, agpat8 antikoerper, alcat1 antikoerper, 1agpat8 antikoerper, AGPATP8 antikoerper, 1AGPAT8 antikoerper, AGPAT8 antikoerper, ALCAT1 antikoerper, HSRG1849 antikoerper, UNQ1849 antikoerper, AI181996 antikoerper, Agpat8 antikoerper, Alcat1 antikoerper, Gm91 antikoerper, Lycat antikoerper, RGD1565906 antikoerper, lysocardiolipin acyltransferase 1 antikoerper, lclat1 antikoerper, LCLAT1 antikoerper, Lclat1 antikoerper

Hintergrund: LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
Protein Interaction Partner: LNX1, GOPC, RNF2, UBC, ELAVL1,
Protein Size: 376

Molekulargewicht: 44 kDa

Gen-ID: 253558

NCBI Accession: NM_001002257, NP_001002257

UniProt: Q6UWP7