Derlin-3 Antikörper (C-Term)

Produktnummer ABIN2781869

Produktdetails anti-Derlin-3 Antikörper

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Derlin-3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YYFLEDVFPN QPGGKRLLQT PGFLKLLLDA PAEDPNYLPL PEEQPGPHLP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DERL3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DERL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 235 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Derlin-3

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Andere Bezeichnung: DERL3 (DERL3 Produkte)

Synonyme: 1810006I20Rik antikoerper, 1810063P04Rik antikoerper, IZP6 antikoerper, derlin-3 antikoerper, zgc:63991 antikoerper, C22orf14 antikoerper, LLN2 antikoerper, derlin 3 antikoerper, Der1-like domain family, member 3 antikoerper, DERL3 antikoerper, Derl3 antikoerper, derl3 antikoerper

Hintergrund: DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM].
Alias Symbols: C22orf14, IZP6, MGC71803, LLN2, derlin-3
Protein Interaction Partner: ERN1, UBE2J1, SERPINA1, MFI2, AMFR,
Protein Size: 235

Molekulargewicht: 27 kDa

Gen-ID: 91319

NCBI Accession: NM_001002862, NP_001002862

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling