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Osteoactivin Antikörper (N-Term)

GPNMB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781894
  • Target Alle Osteoactivin (GPNMB) Antikörper anzeigen
    Osteoactivin (GPNMB)
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 58
    • 24
    • 23
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 45
    • 14
    Kaninchen
    Klonalität
    • 46
    • 13
    Polyklonal
    Konjugat
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Osteoactivin Antikörper ist unkonjugiert
    Applikation
    • 46
    • 22
    • 13
    • 13
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    KGGRVQAVLT SDSPALVGSN ITFAVNLIFP RCQKEDANGN IVYEKNCRNE
    Homologie
    Cow: 93%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 77%
    Produktmerkmale
    This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
    Top Product
    Discover our top product GPNMB Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 560 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Osteoactivin (GPNMB)
    Andere Bezeichnung
    GPNMB (GPNMB Produkte)
    Synonyme
    HGFIN antikoerper, NMB antikoerper, DC-HIL antikoerper, Dchil antikoerper, ipd antikoerper, glycoprotein nmb antikoerper, glycoprotein (transmembrane) nmb antikoerper, glycoprotein nmb L homeolog antikoerper, Gpnmb antikoerper, GPNMB antikoerper, gpnmb.L antikoerper
    Hintergrund
    GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: HGFIN, NMB
    Protein Interaction Partner: UBC, SMAD4, ITSN2,
    Protein Size: 560
    Molekulargewicht
    60 kDa
    Gen-ID
    10457
    NCBI Accession
    NM_002510, NP_002501
    UniProt
    Q14956
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