SIL1 Antikörper (C-Term)

Produktnummer ABIN2782037

Produktdetails anti-SIL1 Antikörper

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLQQYRQVHL LPGLWEQGWC EITAHLLALP EHDAREKVLQ TLGVLLTTCR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SIL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 461 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SIL1

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Andere Bezeichnung: SIL1 (SIL1 Produkte)

Synonyme: 1810057E01Rik antikoerper, AI042831 antikoerper, wz antikoerper, BAP antikoerper, MSS antikoerper, ULG5 antikoerper, endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae) antikoerper, SIL1 nucleotide exchange factor L homeolog antikoerper, SIL1 nucleotide exchange factor antikoerper, Sil1 antikoerper, sil1.L antikoerper, SIL1 antikoerper

Hintergrund: SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
Alias Symbols: BAP, MSS, ULG5
Protein Interaction Partner: UBQLN1, FBXO6, UBC, SMAD9, CCND3, HSPA5,
Protein Size: 461

Molekulargewicht: 49 kDa

Gen-ID: 64374

NCBI Accession: NM_001037633, NP_001032722

UniProt: Q9H173

Pathways: Unfolded Protein Response, SARS-CoV-2 Protein Interaktom