ACVR2B Antikörper (Middle Region)
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- Target Alle ACVR2B Antikörper anzeigen
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schaf, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ACVR2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KSKNVLLKSD LTAVLADFGL AVRFEPGKPP GDTHGQVGTR RYMAPEVLEG
- Homologie
- Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ACVR2B. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ACVR2B
- Top Product
- Discover our top product ACVR2B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 512 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- Andere Bezeichnung
- ACVR2B (ACVR2B Produkte)
- Synonyme
- ACVR2B antikoerper, XAR1 antikoerper, actr-iib antikoerper, actriib antikoerper, ACTRIIB antikoerper, ActR-IIB antikoerper, HTX4 antikoerper, ActRIIB antikoerper, actr2b antikoerper, actrIIb antikoerper, wu:fj97d11 antikoerper, activin A receptor type 2B antikoerper, activin A receptor type 2B L homeolog antikoerper, activin A receptor type 2Ba antikoerper, activin receptor IIB antikoerper, ACVR2B antikoerper, acvr2b antikoerper, acvr2b.L antikoerper, Acvr2b antikoerper, acvr2ba antikoerper
- Hintergrund
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Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Alias Symbols: ACTRIIB, ActR-IIB, MGC116908, HTX4
Protein Interaction Partner: GDF2, BMP10, INHBA, PEG10, ERBB2IP, HSP90AA1, SMAD7, SMAD6, SMAD2, IGSF1, SYNJ2BP, SNX6, SNX2, TGFBRAP1, GDF11, MSTN, ACVR1B, SNX1, INHBC, GDF5, INHBB, BMP7, BMP2, ENG, BMP6,
Protein Size: 512 - Molekulargewicht
- 58 kDa
- Gen-ID
- 93
- NCBI Accession
- NM_001106, NP_001097
- UniProt
- Q13705
- Pathways
- Hormone Transport, Cancer Immune Checkpoints
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